| 03/05/2026 23:00 | | Atletico San Luis U19 (W)  | 1 - 1 | Santos Laguna U19 (W) | H |
| 26/04/2026 04:45 | | Santos Laguna U19 (W) | 1 - 0 | Mazatlan FC U19 (W) | T |
| 12/04/2026 04:45 | | Santos Laguna U19 (W) | 1 - 2 | Tigres UANL U19 (W) | B |
| 29/03/2026 04:45 | | Santos Laguna U19 (W) | 0 - 0 | Atlas U19 (W) | H |
| 15/03/2026 04:45 | | Santos Laguna U19 (W) | 2 - 1 | Leon U19 (W) | T |
| 08/03/2026 23:00 | | Mazatlan FC U19 (W) | 2 - 0 | Santos Laguna U19 (W) | B |
| 01/03/2026 04:45 | | Santos Laguna U19 (W) | 1 - 0 | Atletico San Luis U19 (W) | T |
| 15/02/2026 04:50 | | Leon U19 (W) | 0 - 1 | Santos Laguna U19 (W) | T |
| 08/02/2026 04:45 | | Santos Laguna U19 (W) | 3 - 2 | Chivas Guadalajara U19 (W) | T |
| 25/01/2026 22:00 | | Santos Laguna U19 (W) | 4 - 0 | Tijuana U19 (W) | T |
Mexico